International
Astrocyte School

Bertinoro, Italy
26 March - 1 April
2017

 

Programme

  • Sunday, 26 March

    16:30-17:30 Arrival and registration
    17:30 Welcome ceremony
    Introduction to the school, general information, and assignment of students to Agora teams
    18:30 Welcome drinks followed by buffet dinner
  • Monday, 27 March

    9:00-9:45 Alexei Verkhratsky
    Physiology of astroglia
    [30 min + 10 min discussion]
    9:45-10:30 Richard Robitaille
    Excitability of astrocytes: calcium signal
    [30 min + 10 min discussion]
    10:30-10:50 Coffee break
    10:50-11:35 David Attwell
    Astrocyte calcium signalling and neuronal function - is there a connection?!
    [30 min + 10 min discussion]
    11:35-12:20

    Student presentations
    [7 min + 3 min discussion each]

    Stewart Berry (Zurich, Switzerland)
    The hippocampal astrocytic syncytium supports network-wide neuronal synchronization independent of action potentials

    Marco Brancaccio (Cambridge, United Kingdom)
    Astrocytes control circadian pacemaking in mammals via glutamatergic signalling

    Antonio Falasconi (Pisa, Italy)
    Circadian redox oscillations in astrocytes impinge on brain metabolism and memory formation

    Leonidas Georgiou (Okinawa, Japan)
    A novel method for labelling mouse cortical astrocytes in vivo to study astrocyte-neuron interactions

    12:20-12:40 Agora • Preparation (1)
    12:40-14:00 Lunch break
    14:00-14:45

    Student presentations
    [7 min + 3 min discussion each]

    Maralinde Abbink (Amsterdam, The Netherlands)
    The role of astrocytes in early-life stress induced changes in brain structure and function

    Candela González (Madrid, Spain)
    Serotoninergic modulation of neuron-astrocyte signaling

    Sidney Kuo (Minneapolis, MN, USA)
    Activity-dependent regulation of glial glutamate transporter function in the retina

    Marianne Maugard (Fontenay-aux-Roses, France)
    Impairment of L-serine production in astrocytes depletes D-serine and impairs spatial memory

    14:45-15:30 Giorgio Carmignoto
    Optogenetic tools to study in vivo astrocytes
    [30 min + 10 min discussion]
    15:30-16:25

    Student presentations
    [7 min + 3 min discussion each]

    Audrey Denizot (Villeurbanne, France)
    Towards simulation of calcium signaling in fine astrocytic processes

    Sónia Guerra-Gomes (Braga, Portugal)
    The characterization of the neurodevelopmental milestones of the IP3R2KO mouse

    Siddhant Pusdekar (Jupiter, FL, USA)
    The role of astrocyte calcium activity in information processing in the ferret visual cortex

    Román Serrat Reñé (Bordeaux, France)
    Modulation of astroglial calcium signaling by mitochondrial type 1 cannabinoid receptor

    Benedikt Zott (Munich, Germany)
    In vivo large-scale astrocytic calcium waves through a cortical glia-neuron network

    16:25-16:45 Coffee break
    16:45-17:30 Alfonso Araque
    Specific tools for astrocyte stimulation
    [30 min + 10 min discussion]
    17:30-18:15 Marie-Ève Tremblay
    High spatial resolution analyses of glial cells with electron microscopy
    [30 min + 10 min discussion]
    18:15-19:10

    Student presentations
    [7 min + 3 min discussion each]

    Justyna Barut (Krakow, Poland)
    Glucocorticoid receptors in astrocytes participate in modulation of naloxone-induced conditional aversion and withdrawal

    Amber Berdenis van Berlekom (Utrecht, The Netherlands)
    The role of astrocytes in the pathogenesis of schizophrenia

    Laura Caudal (Homburg, Germany)
    Contribution of glial transmitter receptors to pathological network function in mouse models of epilepsy

    Giovanna Crivellaro (Padua, Italy)
    Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2

    Florent Guillebaud (Marseille, France)
    Specific blockade of brain astrocytic connexin 43 hemichannels reduces food intake by activating anorexigenic neuronal circuitry

    20:00 Dinner
  • Tuesday, 28 March

    9:00-9:55

    Student presentations
    [7 min + 3 min discussion each]

    Austin Ferro (Minneapolis, MN, USA)
    Bimodal function of astroglia in spinocerebellar ataxia type 1 disease progression

    Seantel Hopkins (Birmingham, AL, USA)
    Effects of non-aggregating chemically functionalized carbon nanotubes on the morphology and proliferation of D54 human glioma cells

    Raquel Larramona Arcas (Barcelona, Spain)
    ApoE4 astrocytes display alterations in calcium signaling and mitochondrial metabolism

    Marco Matos (Bordeaux, France)
    To a better understanding of ApoE ε4 in the development of synaptic impairment in Alzheimer's disease

    Benjamin Portal (Toulouse, France)
    Unraveling the role of astroglial connexins in depression

    9:55-10:40 Frank Kirchhoff
    Transgenic mouse models for astrocyte and NG2 glia research
    [30 min + 10 min discussion]
    10:40-11:10 Coffee break
    11:10-12:35

    Student presentations
    [7 min + 3 min discussion each]

    Mattia Di Paolo (L'Aquila, Italy)
    Microglia activation in pathological retinal conditions

    Stefanie Götz (Munich, Germany)
    Characterization of ion channels in astrocytes proliferating in response to acute brain injury

    Alwin Kamermans (Amsterdam, The Netherlands)
    Enhanced astroglial TRPM7 expression in multiple sclerosis lesions compromises neuronal morphology

    Coralie-Anne Mosser (Paris, France)
    Microglial cells regulate the functional maturation of synapses in the somatosensory cortex during postnatal development

    Morgane Roche (Paris, France)
    Two-photon lifetime imaging of oxygen consumption in glomerular network

    Julie Savage (Quebec, QC, Canada)
    Microglial dysfunction in Huntington's disease

    Elsa Tremblay (Montreal, QC, Canada)
    Motor-unit specific synaptic changes at the neuromuscular junction in an ALS mouse model

    Francesco Trovato (Pisa, Italy)
    A versatile reporter system for KO mosaic generation in vivo

    12:35-14:00 Lunch break
    14:00-14:45 Dorothy Schafer
    Capturing microglia in action: live imaging to molecular dissection of function
    [30 min + 10 min discussion]
    14:45-15:40

    Student presentations
    [7 min + 3 min discussion each]

    Sebastiano Curreli (Genoa, Italy)
    Transcriptional mechanisms mediating direct lineage conversion of astrocytes to induced dopaminergic neurons

    Tiago Henriques (Trieste, Italy)
    Functional role of the calcium-activated chloride channel TMEM16A in supporting cells of the mouse olfactory epithelium

    Bas Lendemeijer (Rotterdam, The Netherlands)
    Rapid specification of human pluripotent stem cell derived neural progenitors to transplantable astrocytes to study familial depression

    Svetlana Mastitskaya (London, United Kingdom)
    The role of astroglial 5-HT2A receptors in processing of afferent information at the level of NTS

    Joanna Sowa (Krakow, Poland)
    Modulation of potassium currents in primary astroglia cultures by prenatal stress and dexametasone

    15:40-19:00 Agora • Preparation (2)
    [with coffee]
    20:00 Pizza party
  • Wednesday, 29 March

    9:00-9:45 Elly Hol
    Astrocytes in health and disease: tools to study molecular changes
    [30 min + 10 min discussion]
    9:45-10:30 Dorothy Schafer
    Microglia-dependent mechanisms governing neural circuit plasticity
    [30 min + 10 min discussion]
    10:30-11:00 Coffee break
    11:00-11:45 David Attwell
    Membrane currents and calcium transients in microglia
    [30 min + 10 min discussion]
    11:45-12:30 Keith Murai
    Creating astrocyte diversity in the brain
    [30 min + 10 min discussion]
    12:30-14:00 Lunch break
    14:00 Departure to Ravenna
    Sightseeing and guided tours, followed by dinner
    Return to Bertinoro after dinner
  • Thursday, 30 March

    9:00-9:45 Hajime Hirase
    Role of astrocytic calcium elevation in transcranial direct current stimulation in mice
    [30 min + 10 min discussion]
    9:45-10:30 Giovanni Marsicano
    Behavioral roles of astroglial CB1 receptors
    [30 min + 10 min discussion]
    10:30-11:00 Coffee break
    11:00-11:45 Giorgio Carmignoto
    Unique properties of the astrocyte response to gabaergic interneurons
    [30 min + 10 min discussion]
    11:45-12:30 Eric Newman
    Astrocyte regulation of blood flow: fact or fantasy?
    [30 min + 10 min discussion]
    12:30-14:00 Lunch break
    14:00-14:45 Frank Kirchhoff
    (Patho)-Physiological properties of astrocytes in vivo
    [30 min + 10 min discussion]
    14:45-15:30 Alfonso Araque
    Circuit-specific synaptic regulation by astrocytes
    [30 min + 10 min discussion]
    15:30-19:00 Agora • Preparation (3)
    [with coffee]
    20:00 Dinner
  • Friday, 31 March

    9:00-9:45 Alexei Verkhratsky
    Principles of astrogliopathology with emphasis on neurodegenerative diseases
    [30 min + 10 min discussion]
    9:45-10:30 Elly Hol
    Reactive astrocytes in brain disease: do they affect neuronal communication?
    [30 min + 10 min discussion]
    10:30-11:00 Coffee break
    11:00-11:45 Marie-Ève Tremblay
    Roles of microglia at synapses in health and disease
    [30 min + 10 min discussion]
    11:45-12:30 Richard Robitaille
    Decoding the functional state of the neuromuscular junction by glial cells in health and disease
    [30 min + 10 min discussion]
    12:30-14:00 Lunch break
    14:45-19:00 Agora
    [with coffee]
    19:00-19:30 General discussion, Concluding Remarks, Questionnaires
    20:00 Farewell Dinner
  • Saturday, 1 April

      Departure